IDEO: The skincare brand was inspired by the breakthrough research of Dr. John Blass, MD, PhD, who dedicated more than 30 years of his career to Alzheimer's research with an exquisitely simple approach: helping cells remember. His discovery of RMA (resveratrol, malate, and antioxidants) changed the landscape of neurological research by crossing the almost impenetrable blood-brain barrier to help brain cells regenerate their capacity to function. On a cellular level, skin tissue shares many of the same properties as brain tissue. Skin aging is characterized by wrinkling, loss of elasticity, laxity, and a rough-textured appearance, while in brain aging, metabolism slows down, oxidation proceeds unchecked, and DNA mitochondrial mutation multiplies. As aging occurs, it's as if cells forget how to function, whether in the brain or the skin cells; the Krebs cycle slows down, leading to an increase in free radicals.