Key Takeaways:111SKIN, a luxury clinical skincare brand, landed a minority investment from Estée Lauder Companies.111SKIN was a 2024 BeautyMatter FUTURE50 brand.Dr. Yannis Alexandrides will remain actively involved in the brand and will continue to lead the business. 111SKIN operates in a fast-growing segment where medical expertise and powerful high-performance formulations are shaping consumer demand.WHO: Founded in 2012, 111SKIN was originally developed by renowned plastic and reconstructive surgeon Dr. Yannis Alexandrides to accelerate his patients’ healing. At the heart of the brand is its innovative NAC Y2, a pioneering complex designed to support skin repair and maintain a healthy, radiant, and resilient complexion. Building on this clinical expertise, 111SKIN has developed a portfolio of more than 30 products, anchored by its Black Diamond and Reparative collections, priced from $50 to $1,000. The brand distributes through luxury retail, e-commerce, and high-end spa channels, including Harrods, Bluemercury, Nordstrom, Mandarin Oriental, and Aman.The Estée Lauder Companies is a global leader in prestige beauty, founded in 1946 and headquartered in New York City. The company’s products are sold in approximately 150 countries and territories under brand names including: Estée Lauder, Aramis, Clinique, Lab Series, Origins, MAC, La Mer, Bobbi Brown Cosmetics, Aveda, Jo Malone London, Bumble and bumble, Darphin Paris, Tom Ford, Smashbox, Aerin Beauty, Le Labo,  Glamglow, Kilian Paris, Too Faced, Editions de Parfums Frédéric Malle, Dr.Jart+, the Deciem family of brands, and Balmain Beauty.