Spas across the globe are stepping up their game. With the Global Wellness Institute predicting that the global wellness tourism industry will be worth $9 trillion by 2028 and the global spa services market valued at $99.79 billion in 2024 according to Fortune Business Insights, there’s certainly an audience to be captured. Organizations like nonprofit  Hevolution Foundation have committed to $1 billion annually to drive aging research forward. Forbes reports that longevity and anti-aging start-ups saw nearly $2 billion in venture capital funding in 2021, a two-fold increase from the previous year.

A desire to not just live longer but better is the fuel to that booming market, with longevity and antisenescence therapies estimated to reach $44.2 billion by 2030. The tools for those therapies can be derived from ancient practices like Ayurveda, high-tech tools like 3D body imaging, or niche medical routes like stem cell injections. Receiving these treatments in lavish surroundings that are as pleasing to the eye as they are to the mind is showing customers that they can have the best of both worlds: a tranquil setting and top-tier scientific innovation.

From the UK to Mexico, BeautyMatter rounds up the most luxurious spas offering science-backed treatments for the wellness travelers of today and tomorrow.

Maxx Wellbeing Centre

Maxx Royal Bodrum Resort

Turkey

This 5,750-square-meter (61,892-square-foot) space spans 21 treatment rooms, 2 bespoke spa suites, plus a longevity center with 11 rooms. Wellness protocols are overseen by in-house resident doctor, Dr. Buğra Öktem who specializes in Ayurvedic medical methods. Offers include an ozone sauna, cryotherapy, a Nuvola floating sleep bed (a zero-gravity dry floatation bed with hydro massage), a floatation pool, and SCIO quantum testing (a biofeedback system for stress reduction). Wellness packages include a 14-day Ayurvedic detox for €10,000 ($10,406) and a 7-day natural healing program including reflexology, Tibetan sound therapy, and Indian sound massage for €2,025 ($2,107). Brands used for facial and body treatments include Biologique Recherche and Santa Maria Novella.

Grand Resort Bad Ragaz

Switzerland

First opened in 1869, Grand Resort Bad Ragaz has been a leading wellness oasis with 9 saunas, 10 medical departments, a 92,500-square-foot spa with thermal pools, plus 30 doctors on standby. In January 2023, the five-star resort underwent a $14.8 million renovation project. Offers include hyperbaric oxygen therapy, which provides the body with up to 14 times more oxygen for a stronger immune system and faster wound healing, as well as targeted packages using the spa’s NEWYOU Method, which blends holistic and medicine-based wellness methods. For example, the Smart Aging package for CHF 5,050 ($5.556) for five days (excluding overnight stay), encompasses skin analysis, vitamin-shot infusions, ozone therapy treatments, and Geneo skin treatments (which combine exfoliation, skin oxygenation, and facial rejuvenation).

Lefay Resort & Spa Dolomiti 

Italy

Set among the Dolomite mountains, this spa and resort blends a majestic view with Eastern therapeutic principles. Bathers can swim in a saltwater lake and salt grotto. Its 1,700-square-meter (18,298-square-foot) sauna area is divided into four different sections: The Green Dragon, The Red Phoenix, The White Tiger, and The Black Tortoise. Each has a custom humidity, temperature, and dedicated phyto and aromatherapies, developed according to principles of Classical Chinese Medicine, with sequences ranging from €135 to €330 ($140-$343) in price.

Chenot Palace Weggis

Switzerland

Named after the French doctor Henri Chenot who claimed that with the right care, the human body could live to 120 years of age, the Chenot Palace Weggis makes longevity a core pillar of its offerings. The space’s flagship 7-day retreat, costing CHF 7,100 ($7,825) begins with several assessments like a diagnostic for Chenot Lifestyle biomarkers including vascular age assessment, minerals and heavy metals intoxication analysis, and skin collagen thickness assessment. Treatments include bioenergetic treatments, hypoxic exercise training, and Neurac treatments, which help counteract abnormalities in muscle function through neuromuscular system stimulation.

Eynsham Baths at Estelle Manor

United Kingdom

Nestled into the scenic Cotswolds and five years in the making, the Eynsham Baths is a 3,000-square-meter (32,291-square-foot) neoclassical Roman bath-inspired space featuring a tepidarium bathing hall, five thermal pools, ten treatment rooms, and a lounge.

The space offers a 180-minute Thermal Journey (£95, $118) encompassing six different thermal areas, designed using clinical research by  Dr. Andrew Huberman and Dr. Susanna Søberg on thermodynamics, cold water, and contrast therapy in order to stimulate the metabolic rate and immune system while soothing the nervous system.

Other treatments include a Chi Nei Tsang stomach massage and Indian potli massage with Ayurvedic herbs. There are also 50-minute Wim Hof Method Breathwork sessions offered, performed in a dedicated outdoor marble pool, and sound healing ceremonies performed in The Shala, a separate holistic studio.

SHA Wellness Clinic Mexico

Mexico

The second clinic founded by father-son duo Alfredo Bataller Parietti and Alejandro Bataller (the first iteration was set up in Alicante, Spain in 2008), SHA Wellness Clinic offers treatments like ozone IVs, virtual-reality workouts, stem cell injections, binaural brain treatments, and transcranial electric stimulations alongside genetic testing. Described as “the very first large-scale medical spa in the Americas,” there are 5 onsite doctors, 100 treatment rooms spread over 6 floors, including an advanced cell regeneration therapy machine normally reserved for oncology centers that transmits static charges, electrons, and anions around the entire body to boost energy levels. The company was born out of Parietti’s personal experience of recovering from cancer through the use of a macrobiotic diet and alternative therapies. Its most extensive testing package includes an analysis of polymorphisms in 86 genes, covering risks like obesity, osteoporosis, and emotional health. Its weeklong Well-Ageing and Prevention program costs $8,250, and the clinic also offers specialized packages ranging from gut health ($1,600) to sexual well-being ($2,200).

Mount Med Resort

Austria

After undergoing a  £62 million ($77 million) renovation, this resort in the Alpine village of Oberau has a 37-room medical center with programs like the 7-night Healthy Beauty program, which starts from €4,094 ($4,264) per person. Dr Alexander Papp, an Austrian aesthetics and reconstructive surgeon, founded the institute following a decade of research and feedback from 1,500 clients on improving their general health. Treatments include 3D body imaging, metabolic testing, soundwave therapies, and  NAD+ infusions.

Soneva Fushi

Maldives

With the first retreat opened in 1995, the company’s offerings blend ancient healing modalities like Traditional Chinese Medicine, herbalism, and Ayurveda with more modern approaches like ozone therapy, cryotherapy, and hyperbaric oxygen therapy. Six doctors, from Ayurvedic to naturopathic, work on-site. It is also the only stem cell center in the country. Under the Soneva Soul wellness concept, 14-Day Time Rewind Programme, which includes NAD IV therapy and Prolozone regenerative medicine injections, starts at $15,821. Co-founders Sonu Shivdasani and Eva Malmström Shivdasani also created the Six Senses Resorts & Spas in 2004, later selling the company in 2012 to Pegasus Capital Advisors for an undisclosed amount. The company also has strong sustainability roots, banning branded bottled water across its resorts in 2010 and introducing a mandatory carbon levy in 2012 to offset the impact of all guest stays, which has funded the planting of half a million trees in Thailand.

Canyon Ranch

United States

Based in Tucson Arizona, Canyon Ranch launched its Longevity8 program in August of 2024. A 4-day experience encompassing 18 consultations with experts including neuropsychologists and performance scientists, the $20,000 program includes over 15 diagnostic tests and 200 biomarkers to individualize treatment plans. Vascular ultrasound, DEXA (dual-energy x-ray absorptiometry) body composition scans, and overnight sleep screenings are included in the package.

Clinique La Prairie Anji Health Resort 

China

A 138,251-square-foot space, created in partnership with Sunjoy Group, the resort offers 7 villas with 29 rooms and suites. The treatments are built around a four-pillar (medical, wellness, movement, nutrition) CLP Longevity Method.

A treatment exclusive to this Shanghai location (its Swiss headquarters offer similar treatments like a 7-day Brain Potential program for CHF 26,900 ($29,439)), the Reverse Aging Premium program costs 449,000 CNY ($61,609). The weeklong program includes immunocellular stimulation, DNA Testing, brain MRI scans, and antioxidant injections.

Dharana Wellness Retreat

India

Located in the heart of the Sahyadri Mountains, the 2,500-acre property offers programs spanning up to three weeks, incorporating a range of practices from polysomnography, and genetic or biomarker testing to counseling, music therapy, and energy cleansing. A core part of the retreats practices are based in Ayurveda.

Its 5- or 7-night Dharana Mental Resilience Retreat (the latter of which costs approximately $3,699 including transfer and accommmodation) is structured to alleviate mental health conditions like anxiety, depression, and post-traumatic stress through cortisol reduction, endorphin boosting, and melatonin level balancing. Treatments include analyzing of oxidative stress and toxin build up in the body to determine the best course of treatment, followed by psychosomatic and immunity focused treatments.

Daharana Wellness Retreat’s programs are built on the pillars of exercise physiology, nutrition and dietetics, conflict resolution, preventative medicine, and spiritual well-being.